-
Cryo-EM structure of Csm-crRNA-target RNA ternary bigger complex in complex with cA4 in type III-A CRISPR-Cas system
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Cryo-EM structure of Csm-crRNA-target RNA ternary bigger complex in complex with cA4 in type III-A CRISPR-Cas system. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and...
- Subject
-
Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsCryoelectron MicroscopyProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, TertiaryRibonucleases / chemistry
- Access Rights
- Free to All
-
Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included...
- Subject
-
Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsCryoelectron MicroscopyProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, TertiaryRibonucleases / chemistry
- Access Rights
- Free to All
-
Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with AMPPNP in type III-A CRISPR-Cas system
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Csm-crRNA-target RNA ternary complex in complex with AMPPNP in type III-A CRISPR-Cas system. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included...
- Subject
-
Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsCryoelectron MicroscopyProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, TertiaryRibonucleases / chemistry
- Access Rights
- Free to All
-
Regulation of the error-prone DNA polymerase polκ by oncogenic signaling and its contribution to drug resistance
- Authors
- Campbell, NathanielWhite, Richard Mark
- Description
Summary from the GEO: "We report how the A375 melanoma cell line changes following CRISPR-Cas9 inactivation of POLK RNA-seq of A375 melanoma cells following CRISPR-Cas9 with either POLK sgRNA or non-targeting control sgRNA (N=3 replicate samples each)." Abstract summary From "Regulation of the error-prone DNA polymerase Polκ by oncogenic signaling and its contribution to drug resistance": "The DNA...
- Subject
-
Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsMelanoma
- Access Rights
- Free to All
-
Cryo-EM structure of Csm-crRNA binary complex in type III-A CRISPR-Cas system
- Authors
- Jia, NingWang, ChongyuanEng, Edward T.Patel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Cryo-EM structure of Csm-crRNA binary complex in type III-A CRISPR-Cas system. The main summary display for this entry includes information on the experimental method, protein source, macromolecules and small molecules included in the deposit,...
- Subject
-
CRISPR-Cas SystemsRNA-Binding Proteins
- Access Rights
- Free to All
-
Cryo-EM structure of ternary Csm-crRNA-target RNA with anti-tag sequence complex in type III-A CRISPR-Cas system
- Authors
- Jia, NingWang, ChongyuanEng, Edward T.Patel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Cryo-EM structure of ternary Csm-crRNA-target RNA with anti-tag sequence complex in type III-A CRISPR-Cas system. The main summary display for this entry includes information on the experimental method, protein source, macromolecules and small...
- Subject
-
CRISPR-Cas SystemsRNA-Binding Proteins
- Access Rights
- Free to All
-
Cryo-EM structure of larger Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system
- Authors
- Jia, NingWang, ChongyuanEng, Edward T.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Cryo-EM structure of larger Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system. The main summary display for this entry includes information on the experimental method, protein source, macromolecules and small molecules included...
- Subject
-
CRISPR-Cas SystemsRNA-Binding Proteins
- Access Rights
- Free to All
-
Cryo-EM structure of Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system
- Authors
- Jia, NingWang, ChongyuanEng, Edward T.Patel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Cryo-EM structure of Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system. The main summary display for this entry includes information on the experimental method, protein source, macromolecules and small molecules included in...
- Subject
-
CRISPR-Cas SystemsRNA-Binding Proteins
- Access Rights
- Free to All
-
Crystal structure of Csm1-Csm4 subcomplex in the type III-A CRISPR-Csm interference complex
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Crystal structure of Csm1-Csm4 subcomplex in the type III-A CRISPR-Csm interference complex. The main summary display for this entry includes information on the experimental method, protein source, macromolecules and small molecules included in...
- Subject
-
CRISPR-Cas SystemsRNA-Binding Proteins
- Access Rights
- Free to All
-
Cryo-EM structure of AcrVIA1-Cas13(crRNA) complex
- Authors
- Jia, NingMeeske, Alexander J.Marraffini, Luciano A.Patel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Cryo-EM structure of AcrVIA1-Cas13(crRNA) complex. The main summary display for this entry includes information on the experimental method and validation, macromolecules and version history. Data is provided for download as FASTA sequence format,...
- Subject
-
Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Associated ProteinsCRISPR-Cas SystemsDNA-Directed RNA PolymerasesListeria
- Access Rights
- Free to All